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SIS
+++-- stay in school
++/-- special isotope separator
+/--- safety injection system
AcroLexic: Dictionary of Acronyms and Abbreviations contains 36 more definitions of “SIS”.
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See also

Acronym Definitions
ISIS 17
OASIS 14
CSIS 9
ASIS 7
MSIS 7
ASSIST 5
OSIS 5
GENESIS 4
BASIS 4
PSIS 4
SISP 4
BIOSIS 3
SISI 3
FSIS 3
ESIS 3
USIS 2
SISS 2
MASIS 2
DASIS 2
CSISS 2