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OSD
+++++ Office of the Secretary of Defense
/---- On screen display
/---- Office of Systems Development
AcroLexic: Dictionary of Acronyms and Abbreviations contains 7 more definitions of “OSD”.
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See also

Acronym Definitions
OSDH 2
OSDF 2
OSDA 2
EOSD 2
OSDBU 1
EOSDIS 1
FOSDIC 1
OSDIT 1