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OSC
+++++ Orbital Sciences Corporation
++++- On Scene Coordinator
++--- On-Scene Commander
AcroLexic: Dictionary of Acronyms and Abbreviations contains 16 more definitions of “OSC”.
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See also

Acronym Definitions
OSCAR 10
NOSC 6
OSCE 4
SOSC 3
OSCR 3
POSC 3
GOSC 3
WOSC 2
OSCP 2
MOSC 2
TGOSC 2
NCCOSC 2
FOSC 2
EOSC 1
RECOSCIX 1
TOSCA 1
COSCOM 1